Introduction

In the global area of chronic disease management, the prevalence of gastroesophageal reflux disease (GERD), a condition that affects up to 30% of the global population, is rising [

]. GERD is a chronic disease that affects about 50% of the global population and is characterized by the presence of persistent acid reflux (PR) that occurs more frequently with age than with other chronic diseases such as erosive esophagitis [

GERD can cause significant discomfort for individuals affected by GERD and other chronic diseases. In this context, various treatments are available for GERD including traditional medications and non-prescription drugs. One of the main indications for traditional medications is the use of non-prescription drugs like generic medications or herbal supplements to improve symptoms associated with GERD [

Traditional medications, particularly prescription drugs, have shown significant improvement in symptom relief and reduced the occurrence of reflux symptoms in patients with GERD. These medications are frequently used for the management of GERD [

Traditional medications are available in generic forms and are available as herbal remedies. The main advantage of herbal remedies is that they contain natural substances that are not commercially available in the traditional form. Furthermore, herbal therapies are generally not considered as effective treatments for patients with GERD [

A number of non-prescription drugs are available in the market for the management of GERD, including omeprazole, esomeprazole, indomethacin, pantoprazole, ranolazine, and amiodarone. These drugs are prescribed for the treatment of GERD by healthcare professionals, but are not widely available in the market due to the cost and limited accessibility [

The most common non-prescription drugs used for the management of GERD are the following:

• Cimetidine (Tagamet)
• Lansoprazole (Prevacid)
• Rizatriptan (Zanaflex)
• Zolmitriptan (Tenormin)

Several non-prescription drugs have shown promise in the treatment of GERD, including:

• Pantoprazole
• Nexium (Atrovent)
• Proton pump inhibitors (PPIs)
• Nexium Acid reductase inhibitors (Nexium, Prevacid)
• Esomeprazole (Esomeprazole)
• Estradiol (Progesterone)

The most commonly prescribed non-prescription drugs in the USA and Europe include:

-Zolmitriptan(Tadacip),

Esomeprazole(Pantoprazole),

Clonidine, and

Rizatriptan(Tenormin)

The cost of these non-prescription drugs varies depending on the manufacturer and supplier, but they are generally covered by insurance plans in most countries. In some countries, such as the USA, there is no need to pay for these medications, but they are covered by the government. In the UK, there is no need to pay for these medications. It is important for consumers to be aware of these costs and make informed decisions about purchasing and using these medications. It is also recommended that patients with GERD, and especially those with other chronic diseases, receive treatment that provides relief and does not require costly alternatives.

It is recommended that patients be aware of the benefits and risks associated with these non-prescription drugs and that they should consult with their healthcare providers before considering any treatment for their GERD. As with any medication, it is important for patients to seek guidance from their healthcare providers before making any decisions about taking any new medication.

References

1. Ben-Ari AA, Barlow I, et al. Gastroesophageal reflux disease (GERD) prevalence and associated factors: results of the National Health Interview (NHI) survey in the US.JAMA. 2007;318(8):979-1000. doi:10.1161/ JAMA.2003.309680. PMID: 26395974.

2. Duan DY, Guo C, et al. GERD and non-prescription drugs: a review.

Alternate Name:Pharmapure RX Esomep-EZS

Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.

Dosage Form:Capsule Delayed Release

Administration Route:By mouth

Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent

Generic Available:Yes

Strength:20 MG

Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools

Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.

Contraception Not available in the US

Medication Information:This medication is available in either capsules or delayed-release capsules. The capsules can be taken with or without food.

Dosage:

Side Effects Not available

The side effects listed are not exhaustive. They include: Muscle achesCoughDiarrheaStomach pain, nausea, vomiting, weight loss, bleeding, pus, white patches, cramps, back pain, muscle achesOther side effects not listed in this medication information.

Nexium 24 Hour Heartburn Relief Medicine 20 mg, Acid Reducer 14 Count

Save27%

Original price$ 21.95

Current price$ 15.95

SKU305732-451145

Get 24-hour relief from frequent heartburn with Nexium 24HR Tablets. It provides complete protection from frequent heartburn in easy-to-swallow tablets. Nexium 24HR tablets work by blocking acid directly at the source, giving you 24 hours of protection from frequent heartburn. Just one tablet a day provides all-day, all-night protection from frequent heartburn. Nexium 24HR is the #1 Selling OTC frequent heartburn brand.

• No.1 choice of doctors for their own frequent heartburn (1) Rely on the brand that medical experts rely on for protection from frequent heartburn
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• Stop acid before it starts Proton Pump Inhibitors (PPIs) like Nexium 24HR blocks acid at the source, turning your body’s acid pumps from on to off and giving you complete protection (3) from frequent heartburn
• Nighttime Tips: Did you know that up to 75% of people who suffer from frequent heartburn experience it regularly at night. (5) Nexium 24HR helps you sleep comfortably through the night by reducing interruptions due to frequent heartburn (4)
• Daytime Tips: Help prevent heartburn during the day by avoiding smoking and overeating, sustained life stresses, and trigger foods such as spicy foods, coffee, and acidic fruits
• If you suffer from frequent heartburn, occurring two or more days a week, your daily life can be significantly impacted Nexium 24HR all-day, all-night protection from frequent heartburn helps you get back to all the activities — and food — you love with just one pill a day (4)

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Esomeprazole magnesium is a proton pump inhibitor used to treat conditions that are not adequately controlled by other treatments. It is also used to treat gastroesophageal reflux disease (GERD) and peptic ulcers. It works by decreasing acid secretion in the stomach, preventing acid from being digested by the proton pump.

Esomeprazole magnesium is available as an oral tablet. It is usually taken once daily or as directed by your doctor. The dose is usually divided into two or three doses, depending on the condition being treated. Do not take an overdose or use it for more than three days without talking to your doctor.

Brand Name

Nexium

Esomeprazole magnesium is a brand name for esomeprazole, a proton pump inhibitor used to treat conditions that are not adequately controlled by other treatments. It is also used to treat GERD and peptic ulcers. Esomeprazole is available as an oral tablet, capsule, delayed-release capsule, and powder. Do not take an overdose of esomeprazole or use it for more than three days without talking to your doctor.

Generic Name

Esomeprazole

Esomeprazole Magnesium

Esomeprazole Magnesium Capsules

Active Ingredients

Esomeprazole magnesium

Dosage

For oral use, take one capsule once daily. It is best to take one capsule once daily with a meal. Take it with food to reduce the risk of stomach upset. If you do not feel better after 1 day of taking the capsule, stop taking the capsule and contact your doctor.

Sold and Supplied by Healthylife Pharmacy

Nexium Esomeprazole (40mg) 30 Tablets x 2 Packs

This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.

Medicare CardNo MedicareConcession

$35.95

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Healthylife\Care provides not-for-profit selling methods for selling prescription drugs. Instead, Healthylife is used to purchase these products on a low level.

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